Download the PDF to view the article, as well as its associated figures and tables. To the Editor. My comments will be limited to the subject of the author's remarks about Rinkel's intracutaneous serial dilution endpoint titration SET. Rinkel, in the early s, became interested in Hansel's observation that patients relieved of hay fever symptoms by maximum tolerated doses of pollen extracts could also be relieved by lower "optimal" doses.
This was more economical, and the chance of producing alarming systemic reactions was less. Rinkel found that dilutions for SET were preferred because they more closely approximated changes in skin sensitivity.
Serial dilution end-point titration "enabled one to determine the end-point of reaction. It gave the user a method of making an exacting as well as a specific diagnosis Ruddy LW. Intracutaneous Serial Dilution End-point Titration. Coronavirus Resource Center. Our website uses cookies to enhance your experience.
By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy Continue. Twitter Facebook. This Issue. February 4, Lorenz W. Advanced Allergy Testing also known as SET or Serial Endpoint Titration is currently the most advanced and precise way to test our patients for allergies and produce superior results to relieve you from both seasonal and year-round suffering and discomfort. The first step in getting relief from your allergies is two rounds of simple in-office testing.
Our doctors will advise you to refrain from taking certain medications for a minimum time period before the titration is to be done. During the allergy skin tests a series of small injections using very fine needles is made in rows on your arms. Each reaction is measured and recorded carefully to produce the serums that will be used for your future Serial Endpoint Therapy or allergy shots.
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